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When injected into the tumor, this strain has been shown to increase the concentration of L-arginine within the microenvironment, leading to increased infiltration of tumor-infiltrating T cells, sustained effector T-cell functions, increased tumor-specific T-cell memory formation, and enhanced efficacy of PD-L1-blocking antibodies

Financial support This work was financially supported by the Rational Drug Use Project of Shandong Provincial Pharmaceutical Society (Nos

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18 Also, ROS increase inflammasome activations, which further boost the release of cytokines and tissue damage